Dual functions of codons in the genetic code
نویسندگان
چکیده
منابع مشابه
Evolution of the genetic code. Emergence of stop codons
In my previous study [2] I wrote that the UG base doublet, unlike GU, CU and UC, acquired its meaning after the emergence of adenine. Thus, in my opinion, this base doublet is the first version of a stop codon. In the table of the universal genetic code, this base doublet is a stop codon; moreover, this base doublet encodes cysteine and tryptophan. What could cause the emergence of non-encoding...
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An Unprecedented Non-canonical Nuclear Genetic Code with All Three Termination Codons Reassigned as Sense Codons
A limited number of non-canonical genetic codes have been described in eukaryotic nuclear genomes. Most involve reassignment of one or two termination codons as sense ones [1-4], but no code variant is known that would have reassigned all three termination codons. Here, we describe such a variant that we discovered in a clade of trypanosomatids comprising nominal Blastocrithidia species. In the...
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mRNA translation in many ciliates utilizes variant genetic codes where stop codons are reassigned to specify amino acids. To characterize the repertoire of ciliate genetic codes, we analyzed ciliate transcriptomes from marine environments. Using codon substitution frequencies in ciliate protein-coding genes and their orthologs, we inferred the genetic codes of 24 ciliate species. Nine did not m...
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ژورنال
عنوان ژورنال: Critical Reviews in Biochemistry and Molecular Biology
سال: 2010
ISSN: 1040-9238,1549-7798
DOI: 10.3109/10409231003786094